Solid-Phase Synthesis of O-Phosphorothioylserine- and -threonine-Containing Peptides as Well as of O-Phosphoserine- and -threonine-Containing Peptides

Article abstract of DOI:10.1021/jo00058a006

This paper describes the synthesis of O-phosphorothioylserine, -threonine, and -tyrosine by sulfurization of the intermediate phosphite triester using phenylacetyl disulfide.Several deprotection procedures were investigated to find the optimal conditions