Structure-anticancer and structure-genetic activity relationships of homo- aza-steroidal esters of N,N-bis(2-chloroethyl)aminocinnamic acid isomers

Article abstract of DOI:10.1002/jps.2600820218

Four steroidal lactams of the A- and D-rings were used for the esterification in the C-3 or C-17 positions, respectively, of their nuclei with the N,N-bis(2-chloroethyl)aminocinnamic acid isomers. The condensation reaction of the hydroxylic group of the s