Kinetic resolution of aliphatic 1,2-diols by a lipase-catalyzed sequential acetylation

DOI: 10.1016/S0040-4039(00)60573-7

Source and publish data:

Tetrahedron Letters p. 305 - 306 (1993)

Update date:2022-09-26

Topics:

Authors:

Theil, Fritz

Weidner, Judith

Ballschuh, Sibylle

Kunath, Annamarie

Schick, Hans

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Article abstract of DOI:10.1016/S0040-4039(00)60573-7

The kinetic resolution of 13 racemic aliphatic 1,2-diols (rac-1a-m) by means of a lipase-catalyzed sequential acetylation was investigated. The enantioselectivity of the 3-aryloxy-propane-1,2-diols rac-1a-k depends on the substitution pattern at the aryl ring.

Full text of DOI:10.1016/S0040-4039(00)60573-7

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