Centrally Acting Serotonergic and Dopaminergic Agents. 1. Synthesis and Structure-Activity Relationships of 2,3,3a,4,5,9b-Hexahydro-1H-benzindole Derivatives

DOI: 10.1021/jm00060a014

Source and publish data:

Journal of Medicinal Chemistry p. 1053 - 1068 (1993)

Update date:2022-08-03

Topics:

Authors:

Lin, Chiu-Hong

Haadsma-Svensson, Susanne R.

Lahti, Robert A.

McCall, Robert B.

Piercey, Montford F.

et al. et al.

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Article abstract of DOI:10.1021/jm00060a014

The synthesis and structure-activity relationships (SAR) of 2,3,3a,4,5,9b-hexahydro-1H-benzindole derivatives (3) are described.These compounds are conformationally restricted, angular tricyclic analogs of 2-aminotetralin.The synthesis was achieved in

Full text of DOI:10.1021/jm00060a014

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Product name:cis-2,3,3aS,4,5,9b-hexahydro-9-methoxy-3-(2(R)-methylbenzyl)-1H-benzindole

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