Flexible 1-[(2-aminoethoxy)alkyl]-3-ar(o)yl(thio)ureas as novel acetylcholinesterase inhibitors. Synthesis and biochemical evaluation

DOI: 10.1021/jm00015a020

Source and publish data:

Journal of Medicinal Chemistry p. 2969 - 2973 (1995)

Update date:2022-08-02

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Authors:

Vidaluc Vidaluc

Calmel Calmel

Bigg Bigg

Carilla Carilla

Briley Briley

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Article abstract of DOI:10.1021/jm00015a020

A series of flexible 1-(2-aminoethoxy)-3-ar(o)yl(thio)ureas was synthesized and assessed for antiacetylcholinesterase activity. This series was designed in order to optimize the spacer length linking the two pharmacophoric moieties, i.e., the basic nitrog

Full text of DOI:10.1021/jm00015a020

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