Novel synthesis of substituted c-phenylpiperazines by addition of benzylamine or methylamine to β-nitrostyrene

DOI: 10.1016/S0040-4020(01)90191-7

Source and publish data:

Tetrahedron p. 1391 - 1400 (1993)

Update date:2022-07-30

Topics: Addition reaction Synthetic route Nucleophilic addition Methylamine Reaction Conditions Product Yield Benzylamine Novel Synthesis

Authors:

Mouhtaram

Jung Jung

Stambach

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Article abstract of DOI:10.1016/S0040-4020(01)90191-7

Addition of benzylamine or methylamine to 4-chloro-β-nitrostyrene 2 allowed the successful obtention of 1-phenylethylene-1,2-diamines 5,6. The intermediate nitrocompounds 3,4 were isolated and then reduced in acidic conditions. Selective ethylation of pri

Full text of DOI:10.1016/S0040-4020(01)90191-7

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Product name:N-benzyl-1-(4-chlorophenyl)ethylene-1,2-diamine

Cas No:147461-78-7

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