Aromatase inhibitors: Synthesis, biological activity, and binding mode of azole-type compounds

DOI: 10.1021/jm00062a012

Source and publish data:

Journal of Medicinal Chemistry p. 1393 - 1400 (1993)

Update date:2022-08-03

Topics:

Authors:

Furet Furet

Batzl Batzl

Bhatnagar

Francotte

Rihs Rihs

Lang Lang

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Article abstract of DOI:10.1021/jm00062a012

The enantiomers of the potent nonsteroidal inhibitor of aromatase fadrozole hydrochloride 3 have been separated and their absolute configuration determined by X-ray crystallography. On the basis of a molecular modeling comparison of the active enantiomer

Full text of DOI:10.1021/jm00062a012

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