Synthesis of the methyl thioglycosides of deoxy-N-acetylneuraminic acids for use as glycosyl donors

Article abstract of DOI:10.1016/0008-6215(92)84037-S

Methyl 2-thioglycoside derivatives of 4-, 7-, 8-, and 9-deoxy-N-acetylneuraminic acids have been prepared as glycosyl donors for the synthesis of sialoglycoconjates. Reduction of a (phenoxy)thiocarbonyl group, selectively introduced at the 4 position of m