Condensed heteroaromatic ring systems. XXI. Synthesis of pyrrolo[2,3-d]pyrimidines and pyrrolo[3,2-d]pyrimidines

DOI: 10.1248/cpb.41.81

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 81 - 86 (1993)

Update date:2022-07-30

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Authors:

Sakamoto

Satoh Satoh

Kondo Kondo

Yamanaka

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Article abstract of DOI:10.1248/cpb.41.81

Pyrrolo[2,3-d]pyrimidines and pyrrolo[3,2-d]pyrimidines were synthesized in high yields by the palladium-catalyzed reaction of 4-acetylamino-5-bromopyrimidines and 5-acetylamino-4-iodopyrimidines with (Z)-1-ethoxy-2-(tributylstannyl)ethene followed by cyclization under acidic conditions.

Full text of DOI:10.1248/cpb.41.81

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