Journal of Heterocyclic Chemistry p. 1307 - 1311 (1996)
Update date:2022-09-26
Topics:
Boyer
Fournel
Nicolai
Teulon
A new synthetic route to prepare the 2-hydroxy-5-methyl-7-n-propyl-8-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]m ethyl]-[1,2,4]triazolo[1,5-c]pyrimidine (UP 269-6, Ripisartan) is described. UP 269-6 is a non-peptide angiotensin II antagonist currently in phase
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