New process for the synthesis of UP 269-6, a 1,2,4-triazolo[1,5-c]pyrimidine derivative as a potent orally active angiotensin II antagonist

DOI: 10.1002/jhet.5570330450

Source and publish data:

Journal of Heterocyclic Chemistry p. 1307 - 1311 (1996)

Update date:2022-09-26

Topics:

Authors:

Boyer Boyer

Fournel Fournel

Nicolai Nicolai

Teulon Teulon

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Article abstract of DOI:10.1002/jhet.5570330450

A new synthetic route to prepare the 2-hydroxy-5-methyl-7-n-propyl-8-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]m ethyl]-[1,2,4]triazolo[1,5-c]pyrimidine (UP 269-6, Ripisartan) is described. UP 269-6 is a non-peptide angiotensin II antagonist currently in phase

Full text of DOI:10.1002/jhet.5570330450

Products guided by the article

Product name:5-<(2'-cyanobiphenyl-4-yl)methyl>-4-hydrazino-2-methyl-6-n-propylpyrimidine

Cas No:148474-44-6

R&D Labs maybe for 148474-44-6

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