A short entry into the pyrido[2,3-b] indole ring system. Synthesis of the tetracyclic segment of the marine antitumor agents: Grossularines-1 and -2

Article abstract of DOI:10.1016/S0040-4039(00)60362-3

A new method for the synthesis of substituted pyrido[2,3-b] indoles (α-carbolines) (14, 27-31), featuring Pd-catalyzed cross coupling between pyridine and aniline derivatives and subsequent intramolecular cylization, has been developed. This method provid