Tetrahedron p. 9519 - 9528 (1998)
Update date:2022-08-06
Topics:
Jones, R. Alan
Whitmore, Alexander P.
3,6-Dichloropyridazine and 1-alkyl-3,6-dichloropyridazinium cations react with pyrrolylmagnesium bromide to produce 3-chloro-6-(2- pyrrolyl)pyridazine. Further reaction with other nucleophiles is slow, but is enhanced by quaternisation of the 2-N atom. 3,
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