The synthesis and chemical reactivity of 3-chloro-6-(2- pyrrolyl)pyridazine

DOI: 10.1016/S0040-4020(98)00513-4

Source and publish data:

Tetrahedron p. 9519 - 9528 (1998)

Update date:2022-08-06

Topics:

Authors:

Jones, R. Alan

Whitmore, Alexander P.

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Article abstract of DOI:10.1016/S0040-4020(98)00513-4

3,6-Dichloropyridazine and 1-alkyl-3,6-dichloropyridazinium cations react with pyrrolylmagnesium bromide to produce 3-chloro-6-(2- pyrrolyl)pyridazine. Further reaction with other nucleophiles is slow, but is enhanced by quaternisation of the 2-N atom. 3,

Full text of DOI:10.1016/S0040-4020(98)00513-4

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