Journal of labelled compounds and radiopharmaceuticals p. 905 - 913 (1994)
Update date:2022-08-03
Topics:
Mathis
Enas
Hanrahan
Akgun
The syntheses of the potent and selective serotonin reuptake complex radioligands [123I]- and [125I]5-iodo-6-nitroquipazine (5-iodo-6-nitro-2-piperazinylquinoline) are reported. A seven step synthetic sequence provided the BOC-protected 5-tributyltin-6-nitroquipazine precursor for radioiodination. End of synthesis radioiodination yields of -40% for 123I and ~ 60% for 125I were achieved resulting in labelled products with high specific activities (>4000 and >2000 Ci/mmol, respectively) and radiochemical purities (>98%).
View MoreMedicalChem(Yancheng)Manuf.Co.,Ltd.
Contact:+86-515-84383366
Address:Touzeng BinHai, YanCheng City, JiangSu Province, China
Shijiazhuang Haitian Amino Acid Co., Ltd.
Contact:+86-311-88908111
Address:Shijiazhuang Hebei province,China
Binzhou Holly Pharmaceutical Co.,Ltd.
Contact:74517
Address:No.15 Dapu Road,Huangpu District Shanghai,P.R.China
Contact:13357117572
Address:No.149 Shiji dadao Road.
Chengdu Chengnuo New-Tech Co., Ltd
Contact:0086-028-85749078
Address:4 Jiuyang road,Jiulong industrial port,Chengdu, China
Doi:10.1016/S0040-4039(00)93396-3
(1993)Doi:10.1021/acs.chemrestox.8b00096
(2018)Doi:10.1021/acs.orglett.5b01221
(2015)Doi:10.1016/0008-6215(92)84171-N
(1991)Doi:10.1021/co500022g
(2014)Doi:10.1016/0040-4020(96)00280-3
(1996)