Analogues of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 2. The amide bond 'B-region'

DOI: 10.1021/jm00068a016

Source and publish data:

Journal of Medicinal Chemistry p. 2373 - 2380 (1993)

Update date:2022-07-30

Topics:

Authors:

Walpole Walpole

Wrigglesworth

Bevan Bevan

Campbell

Dray Dray

James James

Masdin Masdin

Perkins Perkins

Winter Winter

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00068a016

A series of compounds incorporating replacements for the amide bond 'B- region' moiety of capsaicin have been synthesized, including vanillylamides and esters, homovanillic acid amides and esters, ureas, and thioureas. These have been tested in an in vitr

Full text of DOI:10.1021/jm00068a016

Products guided by the article

Product name:N-cyano-N'-octyl-O-phenylisourea

Cas No:150059-13-5

R&D Labs maybe for 150059-13-5

Yangzhou Zhongbao Pharmaceutical Co.,Ltd

Contact:+86-514-88290838

Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
JiangXi Keyuan Biopharma Co., LTD.

Contact:+86-563-6833666

Address:Guangde Fine Chemical Zone, Anhui Province, China
Shandong Xingshun New Material Co., Ltd.

website:http://www.sd-xingshun.com

Contact:+86-519-86461196

Address:Middle of Luhua East Road, Dingtao District
Shanghai He Yang International Trading Co., Ltd.

Contact:+86-21-52043598

Address:Room 816, Blag.5, No.58 Huachi Road
SuZhou Ascepion Pharmaceuticals, Inc.(expird)

Contact:0512-86881668

Address:Building C,68Xingqing Road,Suzhou,China.

Relevant to this article

Microwave-assisted C-N and C-S bond-forming reactions: An efficient three-component domino sequence for the synthesis of sulfoether-decorated imidazo[1,2-A]pyridines

Doi:10.1039/c5ra05377c
(2015)
Synthesis of A-seco derivatives of betulinic acid with cytotoxic activity

Doi:10.1021/np049938m
(2004)
O-Allyl Protection of Guanine and Thymine Residues in Oligodeoxyribonucleotides

Doi:10.1021/jo00072a050
(1993)
Decomposition of 2-dialkylaminobenzoyl azides to yield isocyanates and 1,1 -dialky lindazol-1-ium-3-olates

Doi:10.1039/p19960000271
(1996)
Doi:10.1007/BF02682452
(1978)
Practical, Large-Scale Preparation of Benzoxepines and Coumarins through Rhodium(III)-Catalyzed C-H Activation/Annulation Reactions

Doi:10.1021/acs.oprd.9b00191
(2019)

Article Doi