Facile access to 2′-O-acyl prodrugs of 1- (β-D-arabinofuranosyl)-5(E)-(2-bromovinyl)uracil (BVAraU) via regioselective esterase-catalyzed hydrolysis of 2′ 3′, 5′-triesters

DOI: 10.1016/S0040-4039(00)93411-7

Source and publish data:

Tetrahedron Letters p. 3177 - 3180 (1993)

Update date:2022-08-04

Topics:

Authors:

Baraldi, Pier G.

Bazzanini, Rita

Manfredini, Stefano

Simoni, Daniele

Robins, Morris J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)93411-7

Treatment of 1-(2,3,5-tri-O-acetyl-β-_D-arabinofuranosyl) -5-[2-(trimethylsilyl)-vinyl]uracil (3) with pyridinium bromide perbromide and deacetylation gave BVAraU (2). Pig liver esterase (EC 3.1.1.1) catalysed the regioselective hydrolysis of 1-

Full text of DOI:10.1016/S0040-4039(00)93411-7

Products guided by the article

Product name:1-(2,3,5-tri-O-benzoyl-β-D-arabinofuranosyl)-5(E)-(2-bromovinyl)uracil

Cas No:150464-65-6

R&D Labs maybe for 150464-65-6

SHANGHAI SYSTEAM BIOCHEM CO., LTD

website:http://www.systeambc.com

Contact:86-021-58380978

Address:Building 87，Lane 669， Dong Jing Road Shanghai,P.R.China
Shijiazhuang Haotian Chemical Co., Ltd.

Contact:86-311-85044374

Address:293 Donggang Road
QINGDAO HONG JIN CHEMICAL CO.,LTD.

website:http://www.hongjinchem.com

Contact:+86-532-83657313

Address:2ND Building, 8 Shangqing Road, Qingdao, Shandong Province, China.
Shanghai Taibao Pharmaceutical Technology Co., Ltd(expird)

Contact:021-52217366

Address:shanghai
JADECHEM NINGBO CO.,LTD.

Contact:+86-574-89075960

Address:#100 Xiang Yun Road, New High tech area, Ningbo, China

Relevant to this article

Synthesis of the optically active key intermediate of FR901483

Doi:10.1016/j.tetlet.2010.05.089
(2010)
Doi:10.1246/bcsj.40.588
(1967)
Synthesis of Aryl Ketoamides via Aryne Insertion into Imides

Doi:10.1021/acs.orglett.6b00994
(2016)
Doi:10.1039/JR9320001004
()
Synthesis of pentacyclic compounds via intramolecular [3 + 2] photocycloaddition of cycloalkene linked naphthalenes

Doi:10.1016/j.jphotochem.2017.01.008
(2017)
N-substituted piperidinyl alkyl imidazoles: Discovery of methimepip as a potent and selective histamine H₃ receptor agonist

Doi:10.1021/jm049475h
(2005)

Article Doi