Asymmetric reduction of aromatic ketones. I. Enantioselective synthesis of denopamine

DOI: 10.1248/cpb.41.639

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 639 - 642 (1993)

Update date:2022-07-30

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Authors:

Kawaguchi

Saito Saito

Matsuki Matsuki

Iwakuma Iwakuma

Takeda Takeda

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Article abstract of DOI:10.1248/cpb.41.639

Asymmetric reduction of the N-protected amino ketone (2) with several chiral reducing agents, i.e., (R)-(+)-2-amino-3-methyl-1,1-diphenylbutanol (6)-borane complex (method A), (S,S')-N,N'-dibenzoylcystine (7)-LiBH₄-ROH complex (method B), and s

Full text of DOI:10.1248/cpb.41.639

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