Tetrahedron Letters p. 4885 - 4888 (1993)
Update date:2022-08-04
Topics:
Branton
Fields
VanDrisse
Fields
Solid-phase synthesis of an O-palmitoylated peptide has been achieved by either palmitoylation of the resin-bound peptide or synthesis of palmitoylated Fmoc-Thr and subsequent solid-phase incorporation. The desired peptides containing palmitoylated Thr were isolated by reversed-phase C18 HPLC. An O→N acyl shift was encountered when palmitoylated Fmoc-Thr was utilized.
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