Archiv der Pharmazie p. 273 - 278 (1996)
Update date:2022-09-26
Topics:
Capraro, Hans-Georg
Bold, Guido
Faessler, Alexander
Cozens, Robert
Klimkait, Thomas
Lazdins, Janis
Mestan, Juergen
Poncioni, Bernard
Roesel, Johannes L.
Stover, David
Lang, Marc
A series of potent HIV-protease inhibitors has been prepared. Several of the newly synthesized compounds showed high plasma levels after oral administration to animals. Based on the overall biological profile, CGP 61755 was chosen for further preclinical evaluation. For this compound, a 10 step synthesis potentially suitable for large scale production was developed.
View MoreTIANJIN GST CHEMICAL TECHNOLOGY CO., LTD
Contact:+86-22-25210964
Address:Room. 208, No. -12-C, No. 13, Xinbei Road, Tanggu District, New Haixin Area, Tianjin City, China
Jiangxi Huashi Pharmaceutical Co., Ltd
Contact:+86-795-4509628
Address:Ningbo Ave., Fengtian Industrial Park, Fengxin Country, Jiangxi, China.
Hangzhou Showland Technology Co., Ltd.
Contact:86-571-88920516
Address:ROOM2118,NO.553,WENSAN ROAD,HANGZHOU,CHINA
Changzhou Yongxu Chemical Co.,Ltd
Contact:86-0519-85286591
Address:Room 1812,Wanda Plaza B,Xinbei District,Changzhou,Jiangsu,China
Cangzhou Senary Chemical Science-tech Co., Ltd
Contact:+86-317-3563899, 3563699
Address:168 Jinde Road, Cangzhou, Hebei, China
Doi:10.1016/S0277-5387(00)86505-5
(1989)Doi:10.1002/adfm.201202132
(2013)Doi:10.1002/ejoc.201600784
(2016)Doi:10.1021/jacs.5b02775
(2015)Doi:10.1002/adsc.201200695
(2013)Doi:10.1021/acs.joc.9b02073
(2019)
