European Journal of Medicinal Chemistry p. 709 - 714 (1993)
Update date:2022-08-04
Topics:
Laval, J. D.
Roman, V.
Laduranty, J.
Miginiac, L.
Lion, C.
et al.
In the mouse, the intraperitoneal injection of 2-(1-naphthylmethyl)-2-imidazoline has a radioprotective effect even at low doses.Its association with S-<2-(3-aminopropyl)aminoethyl> phosphorothioate (WR 2721) or S-<3-(3-methylaminopropyl)-aminopropyl>phosphorothioate (WR 151327) at low doses led to an ethancement of their respective radioprotective activities without any apparent side effects.These results strengthen the interest of this non-sulphur compound as a radioprotector. radioprotective compounds/phosphorothioates/WR 2721/WR 151327/imidazoline/associations
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Doi:10.1021/jm00029a005
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(1993)Doi:10.1021/acs.orglett.1c00504
(2021)Doi:10.1021/ol403555n
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(1998)
