Substituted O6-benzylguanine derivatives and their inactivation of human O6-alkylguanine-DNA alkyltransferase

DOI: 10.1021/jm00029a005

Source and publish data:

Journal of Medicinal Chemistry p. 342 - 347 (1994)

Update date:2022-08-04

Topics:

Authors:

Chae Chae

McDougall

Dolan Dolan

Swenn Swenn

Pegg Pegg

Moschel Moschel

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Article abstract of DOI:10.1021/jm00029a005

Several new O⁶-benzylguanine analogs bearing increasingly bulky substituent groups on the benzene ring or at position 9 were tested for their ability to inactivate the human DNA repair protein, O⁶-alkylguanine-DNA alkyltransferase. S

Full text of DOI:10.1021/jm00029a005

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