Studies on the biosynthesis of the antibiotic reductiomycin in Streptomyces xanthochromogenus

DOI: 10.1021/ja00079a009

Source and publish data:

Journal of the American Chemical Society p. 12296 - 12304 (1993)

Update date:2022-08-04

Topics: Bioassay Precursor HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) Purification Extraction Fermentation Enzyme Biosynthesis Antibiotic Mutagenesis Polyketide Secondary metabolites Gene cluster LC-MS (Liquid Chromatography-Mass Spectrometry) Transcriptomics Shikimate pathway

Authors:

Cho Cho

Beale Beale

Graff Graff

Mocek Mocek

Nakagawa

Omura Omura

Floss Floss

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Article abstract of DOI:10.1021/ja00079a009

The biosynthesis of the antibiotic reductiomycin (1) in Streptomyces xanthochromogenus was investigated by feeding experiments with radioactive and stable isotope-labeled precursors. NMR and mass spectroscopic analyses of the labeled 1 samples revealed th

Full text of DOI:10.1021/ja00079a009

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