
Journal of the American Chemical Society p. 12296 - 12304 (1993)
Update date:2022-08-04
Topics: Bioassay Precursor HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) Purification Extraction Fermentation Enzyme Biosynthesis Antibiotic Mutagenesis Polyketide Secondary metabolites Gene cluster LC-MS (Liquid Chromatography-Mass Spectrometry) Transcriptomics Shikimate pathway
Cho
Beale
Graff
Mocek
Nakagawa
Omura
Floss
The biosynthesis of the antibiotic reductiomycin (1) in Streptomyces xanthochromogenus was investigated by feeding experiments with radioactive and stable isotope-labeled precursors. NMR and mass spectroscopic analyses of the labeled 1 samples revealed th
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Doi:10.1021/jm00077a007
(1993)Doi:10.1039/c5ta07688a
(2015)Doi:10.1021/ol403495e
(2014)Doi:10.1016/S0040-4039(00)79235-5
(1993)Doi:10.1016/S0040-4039(02)02254-2
(2002)Doi:10.1016/j.bmcl.2016.04.072
(2016)