Convergent synthesis of a key intermediate for hypocholesterolemic agent 1233A, starting from methyl 3-hydroxy-2-methylpropanoate and asymmetrized bis(hydroxymethyl)acetaldehyde (BHYMA*)

DOI: 10.1016/S0040-4039(00)73162-5

Source and publish data:

Tetrahedron Letters p. 4239 - 4242 (1994)

Update date:2022-08-05

Topics:

Authors:

Guanti, Giuseppe

Banfi, Luca

Schmid, Giovanna

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)73162-5

Compound 2, which is a known intermediate for the total synthesis of hypocholesterolemic agent 1233A 1, has been synthesized in good overall yield through a convergent approach, employing 3-hydroxy-2-methylpropanoate 6 and BHYMA* 5 as chiral building bloc

Full text of DOI:10.1016/S0040-4039(00)73162-5

Products guided by the article

Product name:(R)-3-<<(t-butyldimethyl)silyl>oxy>-2-<<<(p-methoxybenzyl)oxy>methoxy>methyl>-1-propanol

Cas No:152669-39-1

R&D Labs maybe for 152669-39-1

C-LAB Chemievermittlung GmbH

Contact:+49-9398-993127

Address:Untertorstr. 27
zhejiang huangyan wanfeng pharm chem co.ltd

Contact:+86-576- 84160728

Address:No. 5 Dazha Road, Economic,Development Zone(JiangKou), Zhejiang, China
Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

website:http://www.bjgreenchem.com/

Contact:+86-427-6515887

Address:301,302, 3rd Floor, Building C-7, Dongsheng Science Park, Northern Territory, Zhongguancun, No. 66, Xixiaokou Road, Haidian District, Beijing
Kaiping Genuine Biochemical Pharmaceutical Co.,Ltd.

Contact:+86-750-2881198

Address:No.1, Xinke Road, Shatang Town, Kaiping, Guangdong Province, P.R.China
Chengdu Biopurify Phytochemicals Ltd.

website:http://www.phytopurify.com

Contact:+86-28-82633397

Address:2F,No.11 Building,No.388 Rongtaidadao CNSTP,Wenjiang Zone,Chengdu,Sichuan, China

Relevant to this article

Stereoselective synthesis of medium-sized cyclic compounds through the intramolecular michael-type reaction utilizing alkyne-hexacarbonyldicobalt complex formation

Doi:10.1246/cl.2007.474
(2007)
Stereospecific synthesis of chlamydocin

Doi:10.1016/S0040-4020(01)88010-8
(1993)
Synthesis of (S)-N-(diphenylphosphinyl)-S-methyl-S-phenyl sulfoximide: A new ligand for asymmetric catalysis

Doi:10.1016/S0957-4166(01)00224-5
(2001)
Catalytic homogeneous oxidation of monoterpenes and cyclooctene with hydrogen peroxide in the presence of sandwich-type tungstophosphates [M₄(H₂O)₂(PW₉O₃₄)₂]^n?, M = Co^II, Mn^II and Fe^III

Doi:10.1016/j.molcata.2016.10.021
(2017)
Synthesis and X-ray Characterization of Alkali Metal 2-Acyl-1,1,3,3-tetracyanopropenides

Doi:10.1021/acs.joc.6b01040
(2016)
Reductive couplings of 2-halopyridines without external ligand: Phosphine-free nickel-catalyzed synthesis of symmetrical and unsymmetrical 2,2'-bipyridines

Doi:10.1021/jo402084m
(2014)

Article Doi