3-Phenylselanylfuran-2(5H)-one: A versatile building block in the synthesis of lignans. A new approach towards 3,4-dibenzyl γ-butyrolactones

DOI: 10.1016/S0040-4020(99)00721-8

Source and publish data:

Tetrahedron p. 12387 - 12398 (1999)

Update date:2022-08-02

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Authors:

Bella, Marco

Piancatelli, Giovanni

Pigro, Maria Cristina

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Article abstract of DOI:10.1016/S0040-4020(99)00721-8

Ready available 3-phenylselanylfuran-2(5H)-one undergoes tandem conjugate addition-alkylation by organocopper reagents to afford, with good yields and diastereoselectivities, 3,4-disubstituted-3-phenylselanyl-γ- butyrolactones, which can be transformed into naturally occurring compounds, such as lignans.

Full text of DOI:10.1016/S0040-4020(99)00721-8

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