Diastereoselective addition of chiral imines and 1,3-oxazolidines with Grignard reagents; asymmetric synthesis of (R)-2-aryl- and (R,R)-2,5-bis(aryl)pyrrolidines

DOI: 10.1016/S0040-4020(01)80819-X

Source and publish data:

Tetrahedron p. 1083 - 1092 (1994)

Update date:2022-08-03

Topics:

Authors:

Higashiyama, Kimio

Inoue, Hiroaki

Takahashi, Hiroshi

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Article abstract of DOI:10.1016/S0040-4020(01)80819-X

Asymmetric syntheses of (R)-2-aryl- and (R,R)-2,5-bis(aryl)pyrrolidines were described starting from chiral aromatic imines derived from (R)-phenylglycinol, in which the diastereoselective additions of Grignard reagents to the chiral imines and 1,3-oxazol

Full text of DOI:10.1016/S0040-4020(01)80819-X

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