Synthesis and inhibitory effects on platelet aggregation of 3-(2-thienyl)- and 3-(1-imidazolyl)-1,2-benzisoxazole derivatives

DOI: 10.1016/0223-5234(94)90129-5

Source and publish data:

European Journal of Medicinal Chemistry p. 75 - 84 (1994)

Update date:2022-08-03

Topics:

Authors:

Nuhrich, A.

Varache-Lembege, M.

Renard, P.

Devaux, G.

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Article abstract of DOI:10.1016/0223-5234(94)90129-5

A series of 3-(2-thienyl)- and 3-(1-imidazolyl)-1,2-benzisoxazoles as well as some isomeric benzoxazoles were synthesized and tested in vitro for their inhibitory effect on arachidonic acid-induced human platelet aggregation.The most active compound (7-me

Full text of DOI:10.1016/0223-5234(94)90129-5

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