Journal of Medicinal Chemistry p. 1646 - 1651 (1994)
Update date:2022-08-05
Topics:
Holmes
Lee
Wijono
Weinkam
Wheeler
Garst
A series of 4-substituted 2-thiophenesulfonamides was prepared from 3- thiophenecarboxaldehyde using metalation chemistry developed for 3- furaldehyde. Several of these compounds inhibit carbonic anhydrase II in vitro at concentrations of less than 10 nM.
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Doi:10.1016/0022-328X(94)87068-3
(1994)Doi:10.1021/ja9530735
(1996)Doi:10.1021/ja500182v
(2014)Doi:10.1021/jm4019178
(2014)Doi:10.1016/j.tetlet.2003.11.082
(2004)Doi:10.1002/hlca.19940770321
(1994)
