
Journal of the American Chemical Society p. 6513 - 6520 (1994)
Update date:2022-07-31
Topics:
Abbott, Shaun D.
Lane-Bell, Patricia
Sidhu, Kanwar P. S.
Vederas, John C.
Substrate analogues were synthesized and examined as inhibitors of diaminopimelic acid (DAP) dehydrogenase from Bacillus sphaericus and of DAP epimerase from Escherichia coli. These enzymes produce meso-DAP (3) (a precursor for L-lysine and for peptidogly
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