Tetrahedron Letters p. 4679 - 4682 (1997)
Update date:2022-08-05
Topics:
Aspinall, Helen C.
Greeves, Nicholas
Lee, Wai-Man
McIver, Edward G.
Smith, Peter M.
15-crown-5 greatly facilitates Williamson ether synthesis when sodium hydride base is used in THF solvent. This mild yet versatile procedure has been employed in the synthesis of new homochiral polyether ligands and bis-allylic ethers which are inaccessib
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