Enantioselective addition of diethylzinc to aldehydes using 2-azanorbornylmethanols and 2-azanorbornylmethanethiol as a catalyst

Article abstract of DOI:10.1016/S0957-4166(97)00118-3

Optically active 2-azanorbornylmethanols and 2-azanorbomylmethanethiol were prepared from ethyl (1S,3S,4R)-2-[(R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene- 3-carboxylate and catalyzed the enantioselective addition of diethylzine to aldehydes to give o