Diastereoselectivity in cyclopropanation and epoxidation reactions of chiral (E)-crotylsilanes: Asymmetric synthesis of substituted tetrahydrofurans

DOI: 10.1016/S0040-4039(00)78244-X

Source and publish data:

Tetrahedron Letters p. 6453 - 6456 (1994)

Update date:2022-08-03

Topics:

Authors:

Panek, James S.

Garbaccio, Robert M.

Jain, Nareshkumar F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)78244-X

Functionalized (E)-crotylsilanes 1 bearing a bis-homoallytic hydroxyl group undergo diastereoselective cyclopropanation and epoxidation reactions to produce substituted tetrahydrofurans 3 and 5 respectively after an acid catalyzed heterocyclization.

Full text of DOI:10.1016/S0040-4039(00)78244-X

Products guided by the article

Product name:(E)-(2R,3R)-3-(Dimethyl-phenyl-silanyl)-2-methyl-hex-4-en-1-ol

Cas No:158587-79-2

R&D Labs maybe for 158587-79-2

SHANGHAI SYSTEAM BIOCHEM CO., LTD

website:http://www.systeambc.com

Contact:86-021-58380978

Address:Building 87，Lane 669， Dong Jing Road Shanghai,P.R.China
Shanghai better-in Medical Technology Co.,LTD.

Contact:+86-21-38921049

Address:Lane 720 zhangjianggaoke cailun road, Pudong, Shanghai, room 513
Zhejiang Kangfeng Chemical Co.,LTD.

Contact:+86-579-86709687

Address:Xueshizhai Industrial Zone, Weishan Town,Dongyang City, Zhejiang Province ,China
Shenyang Xinyihan Chemical Technology Co., Ltd.

Contact:+86-18525026267

Address:362, aigongbeijei street 23 , tiexi district,Shenyang, Liaoning, China
Chemsigma International Co.,Ltd.

website:http://www.chemsigma.com

Contact:86-025-58748998

Address:Rm.705, 15th Building,Rd.Xinke II

Relevant to this article

A Highly Efficient Diversification of 2-Amino/Amido-1,3,4-oxadiazole and 1,3,4-Thiadiazole Derivatives via Reagent-Based Cyclization of Thiosemicarbazide Intermediate on Solid-Phase

Doi:10.1021/acscombsci.5b00140
(2015)
The chemistry of 2H-3,1-benzoxazine-2,4(1H)-dione (isatoic anhydride). 19. Direct formation of 2-aminobenzyl alcohols from the reduction of N-substituted isatoic anhydrides

Doi:10.1002/jhet.5570230145
(1986)
Intramolecular Reactivity of Arylcarbenes: Derivatives of o-Tolylcarbene

Doi:10.1021/jo00093a014
(1994)
Single-step substitution of all the α, β-positions in pyrrole: Choice of binuclear versus multinuclear complex of the novel polydentate ligand

Doi:10.1021/ic5000974
(2014)
Development of potent and selective tissue transglutaminase inhibitors: Their effect on TG2 function and application in pathological conditions

Doi:10.1016/j.chembiol.2015.08.013
(2015)
Doi:10.1016/S0277-5387(00)88157-7
(1994)

Article Doi