A novel class of inhibitors for human steroid 5α-reductase: Phenoxybenzoic acid derivatives. I

DOI: 10.1248/cpb.47.1073

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1073 - 1080 (1999)

Update date:2022-07-29

Topics:

Authors:

Igarashi, Susumu

Kimura, Takenori

Naito, Ryo

Hara, Hiromu

Fujii, Masahiro

Koutoku, Hiroshi

Oritani, Hiroyuki

Mase, Toshiyasu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.47.1073

In a search for novel nonsteroidal inhibitors of human prostatic 5α- reductase, we found anew series of phenoxybenzoic acid derivatives to be potent human prostatic 5α-reductase inhibitors. Among them, 4-(biphenyl-4- yloxy)benzoic acid derivatives (2n, YM

Full text of DOI:10.1248/cpb.47.1073

NII-Electronic Library Service

Products guided by the article

Product name:methyl 4-(biphenyl-4-yloxy)-3-nitrobenzoate

Cas No:158771-27-8

R&D Labs maybe for 158771-27-8

Shreeji pharma international

Contact:0091-265-2313036

Address:311, ATLANTIS HEIGHTS SARABHAI MAIN ROAD,VADIWADI ,VADODARA
xuri chemicals co., ltd

Contact:86-516-66656369

Address:The west road of Huaihai, Xuzhou, China
Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
Yancheng Smiling Imp & Exp Co., Ltd.

Contact:+86-515-83173586

Address:Rm1207, BLD#03, Phoenix Plaza, Juheng Road, Yancheng, Jiangsu, P.R. China
Xiamen Huasing Chemicals Co.Ltd.

Contact:0086-592-6228397

Address:NO.24, Xinglin North 2nd Road,Jimei district

Relevant to this article

A convenient and improved method for the preparation of cyanohydrin esters from acyl cyanides and aldehydes

Doi:10.1055/s-1996-4361
(1996)
Generation of ligand conformations in continuum solvent consistent with protein active site topology: Application to thrombin

Doi:10.1021/jm021028j
(2003)
Synthesis, characterization, and non-volatile memory device application of an n-substituted heteroacene

Doi:10.1002/asia.201301547
(2014)
Efficient routes to isotopically labelled epichlorohydrins ((chloromethyl) oxiranes)

Doi:10.1002/jlcr.2580340908
(1994)
Catalytic asymmetric bromoetherification and desymmetrization of olefinic 1,3-diols with C₂-symmetric sulfides

Doi:10.1021/ja5029155
(2014)
Synthesis and evaluation of novel stearoyl-CoA desaturase 1 inhibitors: 1′-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-3, 4-dihydrospiro[chromene-2,4′-piperidine] analogs

Doi:10.1016/j.ejmech.2010.07.044
(2010)

Article Doi