A novel class of inhibitors for human steroid 5α-reductase: Phenoxybenzoic acid derivatives. I

DOI: 10.1248/cpb.47.1073

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Chemical and Pharmaceutical Bulletin p. 1073 - 1080 (1999)

Update date:2022-07-29

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Authors:

Igarashi, Susumu

Kimura, Takenori

Naito, Ryo

Hara, Hiromu

Fujii, Masahiro

Koutoku, Hiroshi

Oritani, Hiroyuki

Mase, Toshiyasu

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Article abstract of DOI:10.1248/cpb.47.1073

In a search for novel nonsteroidal inhibitors of human prostatic 5α- reductase, we found anew series of phenoxybenzoic acid derivatives to be potent human prostatic 5α-reductase inhibitors. Among them, 4-(biphenyl-4- yloxy)benzoic acid derivatives (2n, YM

Full text of DOI:10.1248/cpb.47.1073

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