A New Pinane-Type Tridentate Modifier for Asymmetric Reduction of Ketones with Lithium Aluminum Hydride

Article abstract of DOI:10.1016/0957-4166(94)00359-J

The reduction of aryl and alkenyl ketones using lithium aluminum hydride modified with (1R,2S,3S,5R)-(+)-10-anilino-3-ethoxy-2-hydroxypinane (3), afforded chiral secondary alcohols in 83-96percent yields and 53-97percent optical yields.The modifier 3 was