Concise General Synthesis of α,γ-Disubstituted β-Amino Ketones from β-Lactams

DOI: 10.1021/jo00097a020

Source and publish data:

Journal of Organic Chemistry p. 5184 - 5188 (1994)

Update date:2022-08-03

Topics:

Authors:

Palomo, Claudio

Aizpurua, Jesus M.

Garcia, Jesus M.

Iturubu, Miren

Odriozola, Jose M.

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Article abstract of DOI:10.1021/jo00097a020

α,γ-Disubstituted β-amino ketones were obtained by ring opening of 3,4-disubstituted N-Boc-β-lactams, promoted by Grignard and organocuprate reagents.

Full text of DOI:10.1021/jo00097a020

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