Concise General Synthesis of α,γ-Disubstituted β-Amino Ketones from β-Lactams

DOI: 10.1021/jo00097a020

Source and publish data:

Journal of Organic Chemistry p. 5184 - 5188 (1994)

Update date:2022-08-03

Topics:

Authors:

Palomo, Claudio

Aizpurua, Jesus M.

Garcia, Jesus M.

Iturubu, Miren

Odriozola, Jose M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00097a020

α,γ-Disubstituted β-amino ketones were obtained by ring opening of 3,4-disubstituted N-Boc-β-lactams, promoted by Grignard and organocuprate reagents.

Full text of DOI:10.1021/jo00097a020

Products guided by the article

Product name:(3R,4S)-3-(Benzyloxy)-1-(tert-butoxycarbonyl)-4-<(S)-2,2-dimethyl-1,3-dioxolan-4-yl>azetidin-2-one

Cas No:160409-00-7

R&D Labs maybe for 160409-00-7

Evershine Chemical CO Ltd

Contact:+86-571-87010026

Address:202, Zhenhua Road,
VanderArk International Limited

Contact:86-10-82437576

Address:Qing He
LINYI FUDE FINE CHEMICAL CO.,LTD

Contact:86-539-2361184

Address:YISHUI, LINYI,SAHNDONG,CHINA
JiangXi Keyuan Biopharma Co., LTD.

Contact:+86-563-6833666

Address:Guangde Fine Chemical Zone, Anhui Province, China
JiangXi Keyuan Biopharma Co., LTD.

Contact:+86-563-6833666

Address:Guangde Fine Chemical Zone, Anhui Province, China

Relevant to this article

Visible-Light Photoredox-Catalyzed C-H Difluoroalkylation of Hydrazones through an Aminyl Radical/Polar Mechanism

Doi:10.1002/anie.201508698
(2016)
Modular syntheses of H₄octapa and H₂dedpa, and yttrium coordination chemistry relevant to ⁸⁶Y/⁹⁰Y radiopharmaceuticals

Doi:10.1039/c4dt00239c
(2014)
Water-promoted ortho-selective monohydroxymethylation of phenols in the NaBO₂ system

Doi:10.1039/c4ob00228h
(2014)
Metal-free aminosulfonylation of aryldiazonium tetrafluoroborates with DABCO×(SO₂)₂ and hydrazines

Doi:10.1002/anie.201309851
(2014)
Organocatalytic entry to chiral bicyclo[3.n.1]alkanones via direct asymmetric intramolecular aldolization

Doi:10.1021/ol051569d
(2005)
Synthesis and pharmacological study of ethyl 1-methyl-5-<2-substituted-4-oxo-3(4H)-quinazolinyl>-1H-pyrazole-4-acetates

Doi:10.1016/0223-5234(94)90033-7
(1994)

Article Doi