Syntheses of racemic and nearly optically pure ether lipids and evaluation of in vitro antineoplastic activities

DOI: 10.1021/jm00050a011

Source and publish data:

Journal of Medicinal Chemistry p. 4147 - 4154 (1994)

Update date:2022-08-04

Topics: In vitro Syntheses Racemic

Authors:

Duclos Jr.

Hwa Hwoy Chia

Abdelmageed

Esber Esber

Fournier

Makriyannis

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Article abstract of DOI:10.1021/jm00050a011

In addition to rac-2-O-methyl-1-O-octadecylglycero-3-phosphocholine (rac- ET-18-OCH₃, rac-Edelfosine, 1), three racemic ether lipid analogs, 4, 5, and 6, were synthesized where N,N-dimethylamino, N-methylpyrrolidino, and N- methylmorpholino gro

Full text of DOI:10.1021/jm00050a011

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