Synthesis of CF3-Substituted Quinolines from β-Chloro-β-trifluoromethyl-vinylaldehydes. I.

DOI: 10.1002/prac.19953370107

Source and publish data:

Journal fur Praktische Chemie - Chemiker-Zeitung p. 34 - 37 (1995)

Update date:2022-08-04

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Authors:

Greif, Dieter

Riedel, Dirk

Feindt, Andreas

Pulst, Manfred

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Article abstract of DOI:10.1002/prac.19953370107

3-(Trifluoromethyl)-acroleines 2 have been synthesized through VILSMEIER's reaction from α-Trifluoromethylketones 1.The reaction of 2 with anilines and naphthylamines gives in good yields 2-trifluoromethylquinolines 4 and benzoquinolines 5.

Full text of DOI:10.1002/prac.19953370107

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Product name:3-trifluoromethylbenzyl trifluoromethyl ketone

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