A Novel and Concise Synthesis of Aminocyclopentitols and 1-Deoxynojirimycin via Radical Cyclization of Oxime Ethers

Article abstract of DOI:10.1016/0040-4039(94)02185-E

Tributyltin hydride-induced radical cyclization of the oxime ether 3 derived from D-glucose proceeded smoothly to give two amino alcohols 4 and 5 which were converted into two aminocyclopentitol pentaacetates 8 and 12 and 1-deoxynojirimycin known as glyco