Synthesis and Biological Evaluation of Paclitaxel Analogs Modified in Ring C

DOI: 10.1016/0040-4039(95)00431-B

Source and publish data:

Tetrahedron Letters p. 2901 - 2904 (1995)

Update date:2022-07-30

Topics: Synthesis Optimization Structure-Activity Relationship (SAR) Analysis Preclinical and Clinical Development Design and Rationalization Lead Identification

Authors:

Liang, Xian

Kingston, David G. I.

Lin, Chii M.

Hamel, Ernest

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)00431-B

Both 7-deoxy-7α-azidopaclitaxel (6) and 7-deoxy-Δ^6,7-paclitaxel (4) can be prepared from paclitaxel-7-O-triflate (2b).Oxidation of 7-deoxy-Δ^6,7-paclitaxel with dioxirane yields the epoxide 7, while oxidation with osmium tetroxide yie

Full text of DOI:10.1016/0040-4039(95)00431-B

Products guided by the article

Product name:7-deoxy-7-α-azido-paclitaxel

Cas No:165065-03-2

R&D Labs maybe for 165065-03-2

Shuanghe Bio-Technology Limited(expird)

Contact:+86-571-61710758,18968016640

Address:Jinqiao north road 916# Fuyang
changsha chenjin chemical technology co.,LtD(expird)

Contact:86-731-84451263

Address:Room 201/217-218, 101 Jingyuan Electronic Technology Co.,Ltd. Testing Center, No.69, Lufeng Road, High-tech Development Zone, Changsha, China
SHIFANG SUHONG CHEMICAL CO.,LTD

Contact:+86-838-2224563

Address:Room 1207 Zongchen Sunshine No.128 Taishan South Road,Deyang City,Sichuan China
SINO GREAT ENTERPRISE LTD.

Contact:+86-731-84427351

Address:154 JIANXIANG SOUTH ROAD
CGeneTech (Suzhou, China) Co., Ltd.

Contact:+86-512-62956962

Address:Room 101，Bld C11,218 Xinghu Rd.,Suzhou industrial Park

Relevant to this article

Synthesis of divalent β-(1→6)-branched (1→3)-glucohexaose and trivalent β-(1→6)-branched (1→3)-glucotriose

Doi:10.1016/j.carres.2004.09.016
(2004)
Facile fluorination of deoxy-4'-thiopyrimidine nucleosides with 'down' hydroxyl group retention of configuration after fluoride opening of the quaternized N³-MEM anhydronucleosides

Doi:10.1016/S0040-4039(00)78346-8
(1994)
SYNTHESIS OF TETRAHYDRO-1,3-OXAZIN-2-ONES AND -2-THIONES FROM ESTERS OF N-(3-OXOALKYL)CARBAMIC AND -DITHIOCARBAMIC ACIDS

Doi:10.1007/BF01165021
(1994)
Radical Cyclisations of Dienes and Enynes using Phosphorus- and Sulfur-Centered Radicals

Doi:10.1016/S0040-4020(01)89360-1
(1994)
Doi:10.1002/zaac.19562830109
(1956)
Synthesis of optically active myo-inositol derivatives starting from phytic acid

Doi:10.1016/S0008-6215(97)00131-6
(1997)

Article Doi