Regiospecific 4,6-functionalization of pyranosides via dimethylboron bromide-mediated cleavage of phthalide orthoesters

Article abstract of DOI:10.1021/ja00106a021

An efficient strategy for regiocontrolled differentiation of the 4,6-positions of pyranosides has been developed using dimethylboron bromide-mediated cleavage of phthalide orthoesters. The reaction proceeds under mild conditions, is tolerant of additional