Palladium catalyzed reductive deprotection of alloc: Transprotection and peptide bond formation

DOI: 10.1016/0040-4039(95)00449-M

Source and publish data:

Tetrahedron Letters p. 3129 - 3132 (1995)

Update date:2022-07-30

Topics:

Authors:

Beugelmans, Rene

Neuville, Luc

Bois-Choussy, Michele

Chastanet, Jacqueline

Zhu, Jieping

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Article abstract of DOI:10.1016/0040-4039(95)00449-M

N-allyloxycarbonyl group could be efficiently removed using sodium borohydride as hydride donor in the presence of catalytic amount of palladium (0). The conditions were applied to chemoselective protecting group transformation (transprotection) and peptide bond formation.

Full text of DOI:10.1016/0040-4039(95)00449-M

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