Journal of Medicinal Chemistry p. 3789 - 3811 (1994)
Update date:2022-08-02
Topics:
Lowe III
Hageman
Drozda
McLean
Bryce
Crawford
Zorn
Morrone
Bordner
A series of 5-phenyl-3-ureidobenzazepin-2-one cholecystokinin-B (CCK-B) receptor antagonists was synthesized using Beckmann ring expansion of a suitable 4-phenyl-1-tetralone as a key step. Structure-activity relationship studies revealed the importance of
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