Synthesis and characterization of orally active nonpeptide vasopressin V2 receptor antagonists

DOI: 10.1248/cpb.47.501

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 501 - 510 (1999)

Update date:2022-08-03

Topics:

Authors:

Ohkawa, Takehiko

Zenkoh, Tatsuya

Tomita, Masayuki

Hosogai, Naomi

Hemmi, Keiji

Tanaka, Hirokazu

Setoi, Hiroyuki

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Article abstract of DOI:10.1248/cpb.47.501

The present study was undertaken to evaluate whether a novel series of 2,6-diaza-5-oxobicyclo[5.4.0]undeca-1(7),8,10-triene derivatives exhibited antagonistic activity for vasopressin V₁ and V₂ receptors. Most of these compounds were

Full text of DOI:10.1248/cpb.47.501

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