Journal of Organic Chemistry p. 6937 - 6940 (1995)
Update date:2022-08-03
Topics:
Wolf, Eckardt
Spenser, Ian D.
An eight-step synthesis of <2,3-(13)C2>-4-hydroxy-L-threonine <<2,3-(13)C2>-(2S,3S)-2-amino-3,4-dihydroxybutanoic acid> is described, starting from <1,2-(13)C2>acetylene, in an overall yield of 13percent.Since a key intermediate of the synthetic sequence, 4-(benzyloxy)-(Z)-but-2-en-1-ol, is available commercially, the method furnishes a convenient four-step synthesis of nonenriched 4-hydroxy-L-threonine, in an overall yield of 27percent.
View MoreShanghai Sungo Technology Chemical Co., Ltd
Contact:0086-21-51385579
Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
Jiangsu Hualun Chemical Industry Co., Ltd
website:http://www.hualunchem.com
Contact:+86-0514-86464168 86507985
Address:39# Middle Renmin Road, Dinghuo Town
website:http://www.tbbmed.com
Contact:86--21-50498136
Address:Room 6002, Building 7-1, No.160 Basheng Road,Pudong Area,Shanghai China
Sichuan WeiKeqi Biological Technology Co., Ltd.
website:https://www.weikeqi-biotech.com/en
Contact:86-028-81700200
Address:sichuan Chengdu Qingjiang Zhonglu 63号
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
Doi:10.1021/ja01191a051
(1948)Doi:10.1139/v63-323
(1963)Doi:10.1021/jo01148a001
(1950)Doi:10.1021/jo015986p
(2002)Doi:10.1021/ic00130a007
()Doi:10.1021/jo01161a006
(1948)
