Inhibition of matrix metalloproteinases by hydroxamates containing heteroatom-based modifications of the P1' group

DOI: 10.1021/jm00014a010

Source and publish data:

Journal of Medicinal Chemistry p. 2570 - 2581 (1995)

Update date:2022-09-26

Topics:

Authors:

Gowravaram

Tomczuk Tomczuk

Johnson Johnson

Delecki Delecki

Cook Cook

Ghose Ghose

Mathiowetz

Spurlino

Rubin Rubin

Smith Smith

Pulvino Pulvino

Wahl Wahl

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00014a010

In this study, structure-based drug design of matrix metalloproteinase inhibitors [human fibroblast collagenase (HFC), human fibroblast stromelysin (HFS), and human neutrophil collagenase (HNC)] was utilized in the development of potent hydroxamates which

Full text of DOI:10.1021/jm00014a010

Products guided by the article

Product name:(R)-3-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-6-benzyloxy-hexanoic acid tert-butyl ester

Cas No:169269-85-6

R&D Labs maybe for 169269-85-6

Hangzhou Yanshan Chemical Co.,Ltd.

Contact:86-571- 87698076

Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
Jinan Jinguilin Chemical Co.,Ltd

Contact:+86-531-81188412

Address:3rd floor of Torch Building, Huanyuan Rd, City of Jinan
ANGCHEN BRIGHTCHEM CO., LTD

website:http://www.angchenchem.com

Contact:+86-510-88302099 82327577

Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China
MS( MAOSHENG )Chemical CO.,LTD

Contact:+86-519-82726678.82726378

Address:TAOXI INDUSTRY ZONE JINTAN
Shanghai chemrole co.,ltd

Contact:021-50278900

Address:No.6,Room 201 ,Lane 299,bisheng road ,shanghai ,china

Relevant to this article

Synthesis of azophenolic crown ethers of C_s symmetry incorporating cis-1-phenylcyclohexane-1,2-diol residues as a steric barrier and diastereotopic face selectivity in complexation of amines by their diastereotopic faces

Doi:10.1039/P19950001429
(1995)
Bis(oxazoline)-ligand-mediated asymmetric [2,3]-Wittig rearrangement of benzyl ethers: Reaction mechanism based on the hydrogen/deuterium exchange effect

Doi:10.1016/j.tet.2012.03.059
(2012)
Copper-catalyzed cascade reaction of 4-iodopyrazole derivatives with amidines for the synthesis of pyrazolo[4,3-d]pyrimidine derivatives

Doi:10.1002/ejoc.201101454
(2012)
Bichromophoric fluorescent photolabile protecting group for alcohols and carboxylic acids

Doi:10.1039/c1pp05317e
(2012)
Fluoro-containing poly(amide-imide)s with sterically hindered pendants: Synthesis and characterization

Doi:10.1016/j.jfluchem.2012.03.009
(2012)
Discovery of Membrane-Bound Pyrophosphatase Inhibitors Derived from an Isoxazole Fragment

Doi:10.1021/acsmedchemlett.9b00537
(2020)

Article Doi