Carbon-14 labelled nitrogen hyeterocycles. The syntheses of three phosphodiesterase inhibitors

DOI: 10.1002/jlcr.2580360910

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 891 - 898 (1995)

Update date:2022-07-31

Topics:

Authors:

Lawrie Lawrie

Novelli Novelli

Saunders

Coates Coates

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Article abstract of DOI:10.1002/jlcr.2580360910

The syntheses of three heterocyclic phosphodiesterase inhibitors are described from a common radiolabelled precursor, namely 2-propoxybenzo[cyano-¹⁴C]nitrile. Conversion of the nitrile to the corresponding methyl ketone or amidine allows elaboration of the heterocycles radiolabelled within ale ring systems.

Full text of DOI:10.1002/jlcr.2580360910

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