A Practical Synthesis of Nonpeptide Cyclic Ureas as Potent HIV Protease Inhibitors

DOI: 10.1016/00404-0399(50)10008-

Source and publish data:

Tetrahedron Letters p. 4967 - 4970 (1995)

Update date:2022-07-31

Topics:

Authors:

Rossano, Lucius T.

Lo, Young S.

Anzalone, Luigi

Lee, Ying-Chi

Meloni, David J.

et al. et al.

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Article abstract of DOI:10.1016/00404-0399(50)10008-

The utilization of the oxydimethylene group to form a trioxepane ring for the protection of 1,2-diols was demonstrated.A process starting with natural L-tartaric acid as the chiral building block is utilized in the synthesis of optically active, nonpeptid

Full text of DOI:10.1016/00404-0399(50)10008-

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