Evaluation of a non-prime site substituent and warheads combined with a decahydroisoquinolin scaffold as a SARS 3CL protease inhibitor

DOI: 10.1016/j.bmc.2018.12.019

Source and publish data:

Bioorganic and Medicinal Chemistry p. 425 - 435 (2019)

Update date:2022-07-30

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Authors:

Ohnishi, Kouji

Hattori, Yasunao

Kobayashi, Kazuya

Akaji, Kenichi

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Article abstract of DOI:10.1016/j.bmc.2018.12.019

A non-prime site substituent and warheads combined with a decahydroisoquinolin scaffold was evaluated as a novel inhibitor for severe acute respiratory syndrome (SARS) chymotrypsin-like protease (3CL^pro). The decahydroisoquinolin scaffold has b

Full text of DOI:10.1016/j.bmc.2018.12.019

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