Total synthesis of brevetoxin B. 2. Second generation strategies and construction of the dioxepane region [DEFG]

DOI: 10.1021/ja00146a009

Source and publish data:

Journal of the American Chemical Society p. 10239 - 10251 (1995)

Update date:2022-08-03

Topics:

Authors:

Nicolaou

Theodorakis

Rutjes Rutjes

Sato Sato

Tiebes Tiebes

Xiao Xiao

Hwang Hwang

Duggan Duggan

Yang Yang

Couladouros

Sato Sato

Shin Shin

Bleckman

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Article abstract of DOI:10.1021/ja00146a009

The second generation strategy for the total synthesis of brevetoxin B (1) is presented. According to this strategy, the heptacyclic [ABCDEFG] phosphonium iodide 4 and the tricyclic [IJK] aldehyde 3 were defined as the precursors for the brevetoxin B skel

Full text of DOI:10.1021/ja00146a009

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