Synthesis of dicarboxymethyl tetraazacyclododecane derivatives for polycondensation

Article abstract of DOI:10.1080/00397919908085901

Three different routes to synthesize selectively protected tetraaza macrocycles bifunctionalized with carboxymethyl acid groups have been developed in order to obtain monomers for polycondensation. The first way has been carried out from cyclen, whose synthesis has been improved, requires 6 steps. The second way allowed to obtain the bifunctional protected macrocycle from ethylenediamine and diethyl iminodiacetate in 2 steps. The last way has consisted in synthesizing directly a monomer by cyclization from ethylenediaminetetraacetic acid bisanhydride and ethylenediamine.

Full text of DOI:10.1080/00397919908085901

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Synthesis of Dicarboxymethyl
Tetraazacyclododecane Derivatives
for Polycondensation
V. Montembault a , H. Mouaziz a , V. Blondeau a , R. Touchard
a , J.-C. Soutif a & J.-C. Brosse a
a Laboratoire de Chimie Organique Macromoléculaire UMR-
CNRS-6515, Chimie et Physique des Matériaux Polymères
Avenue Olivier Messiaen, F-72085, LE MANS Cedex 09,
France
Published online: 17 Sep 2007.
To cite this article: V. Montembault , H. Mouaziz , V. Blondeau , R. Touchard , J.-C. Soutif
& J.-C. Brosse (1999): Synthesis of Dicarboxymethyl Tetraazacyclododecane Derivatives
for Polycondensation, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 29:23, 4279-4294
To link to this article: http://dx.doi.org/10.1080/00397919908085901
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