Chemistry - A European Journal p. 10766 - 10772 (2018)
Update date:2022-08-04
Topics:
Plajer, Alex J.
Ahrens, Lukas
Wieteck, Marcel
Lustosa, Danilo M.
Babaahmadi, Rasool
Yates, Brian
Ariafard, Alireza
Rudolph, Matthias
Rominger, Frank
Hashmi, A. Stephen K.
An unprecedented, often almost quantitative access to tricyclic aromatic compounds by dual gold catalysis was developed. This synthetic route expands the scope of benzofulvene derivatives through a C(sp2)?H bond insertion in easily available starting materials. The insertion takes place with an exclusive chemoselectivity with respect to the competing aromatic C?H positions. A bidirectional synthesis with two competing ortho-aryl C?H bonds in the selectivity-determining step also shows perfect selectivity; this result is explained by a computational investigation of the two conceivable intermediates. The intramolecular competition of two non-equivalent aryl C?H bonds with a benzylic methyl group also showed perfect selectivity.
View MoreSICHUAN TONGSHENG AMINOACID CO.LTD
website:http://www.aminoacid.cc
Contact:86-838-2274206/2850606
Address:Room 1-11-1,No.19 of North TianShan Road,Deyang,Sichuan China
HANGZHOU ZHONGCHANG SCIENTIFIC CO.,LTD
Contact:+86-571-88932183
Address:Hangzhou
website:https://www.sinoshiny.com/products
Contact:+86-20-62802632;62802633
Address:Room 330 GIGCAS Building,No.511 Kehua Street,Tianhe District
Rudong Zhenfeng Yiyang Chemical Co., Ltd.
Contact:0513-84573047
Address:South Fengli Town, Rudong County, Jiangsu Province, China
Zhejiang Chemline International Co., Ltd.
Contact:+86-571-88062298
Address:Hengdian Industry Area, Dongyang, Zhejiang, China
Doi:10.1021/acs.orglett.6b02689
(2016)Doi:10.1002/anie.201404352
(2014)Doi:10.1016/0040-4039(95)01674-7
(1995)Doi:10.1021/ja00149a040
(1995)Doi:10.1021/acs.joc.8b02755
(2019)Doi:10.1016/S0968-0896(98)00172-2
(1998)