Reaction of ruppert's reagent (TMS-CF3) with Oxazolidinones: Synthesis of protected α-amino trifluoromethylketones

DOI: 10.1016/0040-4039(95)01619-S

Source and publish data:

Tetrahedron Letters p. 7761 - 7764 (1995)

Update date:2022-09-26

Topics:

Authors:

Walter, Magnus W.

Adlington, Robert M.

Baldwin, Jack E.

Chuhan, John

Schofield, Christopher J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)01619-S

(Trifluoromethyl)trimethylsilane adds to α-amino acid derived oxazolidin-5-ones in excellent yields. The adducts can be converted into protected α-amino trifluoromethylketones by acid hydrolysis.

Full text of DOI:10.1016/0040-4039(95)01619-S

Products guided by the article

Product name:((S)-1-Benzyl-3,3,3-trifluoro-2-oxo-propyl)-carbamic acid benzyl ester

Cas No:172097-18-6

R&D Labs maybe for 172097-18-6

QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.

Contact:+86 532 80861829

Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Shanghai Zhihua ChemTech Co., Ltd.

Contact:+86-13774313779

Address:Room 817 Suite B 3333 Shenjiang Road
Synchemie Co., Ltd.

website:http://www.synchemie.com/

Contact:+86-574-87642758

Address:Room 901, Yinyi Bund Building， 132 Renmin Road
ZHEJIANG JIANYE CHEMICAL CO.,LTD.

Contact:86-571-64149273,64149234

Address:No. 48, Fuxi Road, Meicheng Town
Hangzhou Yanshan Chemical Co.,Ltd.

Contact:86-571- 87698076

Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China

Relevant to this article

The Synthesis and Thymidylate Synthase Inhibitory Activity of L-γ-L-Linked Dipeptide and L-γ-Amide Analogues of 2-Desamino-2-methyl-N¹⁰-propargyl-5,8-dideazafolic Acid (ICI 198583)

Doi:10.1021/jm00046a014
(1994)
A new method for the preparation of functionalized unnatural α-H-α-amino acid derivatives

Doi:10.1016/j.tetlet.2006.08.096
(2006)
Conformationally Biased Tri- and Di-basic 1,3,5-Triazacyclohexyl Ligands

Doi:10.1039/C39950002361
(1995)
Doi:10.1021/ja00999a024
(1967)
Doi:10.1039/jr9640001992
(1964)
Chemistry of novel compounds possessing multifunctional carbon atoms. X. Synthetic studies of efficient and practical chiral derivatizing agents based on the α-cyano-α-fluorophenylacetic acid structure

Doi:10.1248/cpb.43.1668
(1995)

Article Doi