Reaction of ruppert's reagent (TMS-CF3) with Oxazolidinones: Synthesis of protected α-amino trifluoromethylketones

DOI: 10.1016/0040-4039(95)01619-S

Source and publish data:

Tetrahedron Letters p. 7761 - 7764 (1995)

Update date:2022-09-26

Topics:

Authors:

Walter, Magnus W.

Adlington, Robert M.

Baldwin, Jack E.

Chuhan, John

Schofield, Christopher J.

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Article abstract of DOI:10.1016/0040-4039(95)01619-S

(Trifluoromethyl)trimethylsilane adds to α-amino acid derived oxazolidin-5-ones in excellent yields. The adducts can be converted into protected α-amino trifluoromethylketones by acid hydrolysis.

Full text of DOI:10.1016/0040-4039(95)01619-S

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